منابع مشابه
Beneficial brain autoimmunity?
Markesbery WR. Linguistic ability in early life and cognitive function and Alzheimer's disease in late life. Long-term behavioral and neuroendocrine alterations following chronic social stress in mice: implications for stress-related disorders. Association of education with incidence of cognitive impairment in three established populations for epidemiologic studies of the elderly. Role of the c...
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The trigger that leads to the pathogenesis of type 1 diabetes is currently unknown. It is well established that the pathophysiology of the disease is biphasic. In the first stage, leukocytes infiltrate the pancreatic islets in a response that does not cause damage. In the second phase, which occurs only in diabetes-prone individuals and strains, autoreactive T cells acquire aggressive potential...
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Antigen specific T cells and B cells recognize their target determinants by antigen specific receptors that are being rearranged in a random manner. These cells then undergo negative and positive selection processes that limit, albeit not eliminate, the escape of self-reactive T and B cells capable of eliciting autoimmune responses. The above processes are referred to as "central selection", an...
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methodologies which share the feature of providing some information about the structure or the function of the brain has both clinical and research uses. No one sound in her mind could have doubt about the clinical usefulness of brain imaging. I doubt that anyone would be happy to have brain surgery performed on the basis of a careful neuropsychological evaluation. The situation changes complet...
متن کاملHypothalamic-Pituitary Autoimmunity and Traumatic Brain Injury
BACKGROUND Traumatic brain injury (TBI) is a leading cause of secondary hypopituitarism in children and adults, and is responsible for impaired quality of life, disabilities and compromised development. Alterations of pituitary function can occur at any time after the traumatic event, presenting in various ways and evolving during time, so they require appropriate screening for early detection ...
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ژورنال
عنوان ژورنال: Brain
سال: 2010
ISSN: 0006-8950,1460-2156
DOI: 10.1093/brain/awq206